I have heard that some or all of these points have been discussed in the past, but I am requesting them again as I wasnt around when they were first discussed, and maybe the situation has changed on some points.

Increase the danger of travelling the open roads at night. Currently it is nothing to some folks to hike from Silvy to RM and back in the middle of the night. There are a number of RP opportunities that spring to mind here, more chance meetings in taverns at night time, people may actually use them for lodging, ect, or folks looking to hire on swords for an urgent trip. Adding to this, making some of the small out of the way streets in Silverymoon dangerous at night too, the dont have to be just hostile thieves attacking on sight, ive seen scripts where a couple of thugs demand gold, if you pay, they leave, if not they attack.

Introduce the fatigued and exhausted conditions for characters when they dont sleep. After 18 hours of activity, without a rest you get tired, I havnt been able to locate the reference, but i do remember PnP rules to that effect from one of the editions. (obviously elves will gain something out of this if done correcly)

Food/drink, should be intergrated into the mix somewhere, as a requirment. Perhaps hand in hand with resting or a seperate activity but at least once a day. It opens up a whole new role for hunters/gatherers to provide food and then the rations for sale in shops may actually get used.

Extend sleeping/resting to 8 IG hours (i think this is 56 min real time). Personally I hate when some people set up a tent and "sleep" at an opportune time (through a long convo or while selling /splitting loot), my opnion of camp is that you are in for the long haul. The other thing i find difficult is when my character puts his head down at a reasonable hour, (10pm or so) and is fully rested a hour later ready to march. A mittagator for the long down time could be to shorten the IG hour to 5 min from 7, this would also have the effect of increasing the distances btween towns on the map. (unsure if this is favourable or not, i dont have a scale map handy to tell if the distances are right for travel but currently with a walk speed of 30ft, RM is about 12 miles from SM)
Some (most) of these suggestions may not be popular ones, but they are limiting factors in PnP that give a whole new dimension to the game. Please dont view them as a bundle, it was just easier to put my thoughts down in one post rather than four.